Yazar "Gümüştaş, Seyit Ali" için listeleme
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Are we economically efficient enough to ıncrease the potential of in vitro proliferation of osteoblasts by means of pharmacochemical agents?
İşyar, Mehmet; Gümüştaş, Seyit Ali; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Tosun, Hacı Bayram; Mahiroğulları, Mahir (Bentham Open, 2016)Background: The aim of this study was to test the necessity of using expensive and unaccesible pharmacological-chemical agents in the proliferation of bone tissue cultures and in the induction of mineralized matrix formation ... -
Are we using slow-acting symptomatic chondroprotective drugs conscious enough?
Gümüştaş, Seyit Ali; Öznam, Kadir; Mutlu, Çağrı Ata; Kaya, Yasin Emre; Yılmaz, İbrahim; İşyar, Mehmet; Yıldırım Güzelant, Aliye; Güler, Olcay; Akkaya, Semih; Mahiroğulları, Mahir (Bentham Open, 2017)Background: Osteochondral injuries constitute an entity that is widespread and can be seen in patients of all ages. Actual treatment modalities aim to relieve pain, obtain full range of movement of the joint, and improve ... -
Assessing the negative impact of phenyl alkanoic acid derivative, a frequently prescribed drug for the suppression of pain and inflammation, on the differentiation and proliferation of chondrocytes
Gümüştaş, Seyit Ali; Yılmaz, İbrahim; İşyar, Mehmet; Şirin Yaşar, Duygu; Batmaz, Ahmet Güray; Uğraş, Ali Akın; Öznam, Kadir; Çiftçi, Zafer; Mahiroğulları, Mahir (BMC, 2016)Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed to relieve pain and inflammation. These NSAIDs have also analgesic effects and can be administered via oral, injectable, and topical ... -
Can a biodegradable implanted bilayered drug delivery system loaded with BMP-2/BMP-12 take an effective role in the biological repair process of bone-tendon injuries? A preliminary report
Kömür, Baran; Akyuva, Yener; Karaslan, Numan; İşyar, Mehmet; Gümüştaş, Seyit Ali; Yılmaz, İbrahim; Akkaya, Semih; Şirin, Duygu Yaşar; Mutlu, Çağri Ata; Batmaz, Ahmet Güray; Güler, Olcay; Mahiroğulları, Mahir (Hindawi Ltd, 2017)Background. Use of biodegradable and biocompatible materials in the orthopedic surgery is gaining popularity. In this research, the rate of controlled release of a bilayered prototype biomaterial designed to promote ... -
A case report of osteoblastoma on the distal phalanx of the ring finger successfully treated with curettage and polymethylmethacrylate filling
Gümüştaş, Seyit Ali; Çağırmaz, Talat; Güler, Olcay; Ofluoǧlu, Önder; Kayahan, Sibel (Elsevier, 2015)BACKGROUND: Osteoblastoma is an aggressive benign tumor whose presentation varies with location and size. This rare bone tumor is thus difficult to diagnose particularly when it occurs outside its most common location - ... -
Chondrocyte proliferation, viability and differentiation is declined following administration of methylphenidate utilized for the treatment of attention-deficit/hyperactivity disorder
Gümüştaş, Funda; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Gümüştaş, Seyit Ali; Batmaz, Ahmet Güray; İşyar, Mehmet; Akkaya, Şeyda; Mahiroğulları, Mahir (Sage Publications Ltd, 2017)Purpose: Methylphenidate (MPH) derivative drugs are used because of psychostimulants effects on attention-deficit hyperactivity disorder in children and adults. As far as we know, toxic or anti-proliferative effects of MPH ... -
Does transcription factor, induced by daptomycin and vancomycin, affect HIF-1α, Chondroadherin, and COL2A1?
Karaarslan, Numan; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Özbek, Hanefi; Kaya, Yasin Emre; Akyuva, Yener; Kaplan, Necati; Doğan, Mustafa; Gümüştaş, Seyit Ali; Ateş, Özkan; Erdem, İlknur (Inonu University School of Medicine, 2018)Aim: In this study, it was firstly aimed to investigate the effect of Daptomycin (DAP) on the proliferation in Vancomycin (VCM)-administered primary chondrocyte cultures and non-drug-administered primary chondrocyte cultures. ... -
Evaluation of antibiotic alternatives used in orthopedic departments of 2 hospitals according to rational use of antibiotics
İşyar, Mehmet; Doğan, Mustafa; Gümüştaş, Seyit Ali; Yılmaz, İbrahim; Bilir, Bülent; Güler, Olcay; Saraçoğlu Varol, Gamze; Mahiroğulları, Mahir (Kare Yayıncılık ve İletişim Hizmetleri, 2016)Background: The present study is an analysis of appropriateness of antibiotics use for patients in whom infectious agent was detected. Data from patients in orthopedics and traumatology department of 2 hospitals in the ... -
Femur neck fracture in young adults, is it really an urgent surgery indication: Retrospective clinical study
Gümüştaş, Seyit Ali; Tosun, Hacı Bayram; İşyar, Mehmet; Serbest, Sancar; Öznam, Kadir; Bulut, Güven (African Field Epidemiology Network-Afenet, 2018)Introduction: Femur neck fracture comprises a significant part of intracapsular femur fracture in the intracapsular area of proximal femur and it is mostly seen in elder people. However, these kinds of fractures may be ... -
Iopromide- and gadopentetic acid-derived preparates used in MR arthrography may be harmful to chondrocytes
Öznam, Kadir; Şirin, Duygu Yaşar; Yılmaz, İbrahim; Kaya, Yasin Emre; İşyar, Mehmet; Gümüştaş, Seyit Ali; Özbek, Hanefi; Akkaya, Semih; Kayhan, Arda; Mahiroğulları, Mahir (BMC, 2017)Background: Magnetic resonance arthrography, a procedure through which contrast agents containing gadolinium and/or iopromide are administered intra-articularly, has become a useful tool in musculoskeletal diagnosis. ... -
Konservatif olarak tedavi edilen distal radius kırıklarında kemik mineral dansitesinin fonksiyonel ve radyolojik sonuçlara etkisi
Onay, Tolga; Orak, Mehmet Müfit; Oltulu, İsmail; Çağırmaz, Talat; Gümüştaş, Seyit Ali; Bulut, Güven; Bekler, Halil İbrahim (Galenos Yayıncılık, 2015)Amaç: Bu çalışma, kapalı redüksiyon ve alçılama ile tedavi edilen distal radius kırıklarının, fonksiyonel ve radyografik sonuçları üzerine kemik mineral yoğunluğunun etkisini değerlendirmek üzere tasarlanmıştır. Gereç ve ... -
Surgical treatment of type III acromioclavicular dislocation: Bosworth technique versus hook plating
Gümüştaş, Seyit Ali; Sağlam, Fevzi; Kömür, Baran; Batmaz, Ahmet Güray; Yukunç, İsmail; Tosun, Hacı Bayram; Bekler, Halil İbrahim (Kare Publishing, 2018)OBJECTIVE: In this study, it was compared the clinical results of the Bosworth technique and hook plating in acromioclavicular (AC) dislocations. METHODS: 44 patients are retrospectively evaluated in this study whom diagnosed ... -
Systematic evaluation of drug-loaded hydrogels for application in osteosarcoma treatment
Gümüştaş, Seyit Ali; İşyar, Mehmet; Topuk, Savaş; Yılmaz, İbrahim; Öznam, Kadir; Onay, Tolga; Ofluoğlu, Önder; Mahiroğulları, Mahir (Bentham Science Publ Ltd, 2016)This is a literature review of studies focusing on the preparation of hydrogels for use as oncological drug delivery systems in the treatment of osteosarcoma (OS). The databases of the US National Library of Medicine ...